Pilot it with one PI. Keep it when the lab rotates.
Constructs, primers and notebook entries live in the lab workspace, not with whoever made them. Sequences, maps and notebook entries export in open formats if you ever leave.
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Elsevier2025 research survey
Only45%
of researchers surveyed say they have enough time for research.
View source (opens in a new tab) -
Nature2016 reproducibility survey
More than70%
of researchers surveyed had tried and failed to reproduce another scientist’s experiments.
View source (opens in a new tab)
Design, record and keep it in the lab.
Three jobs every molecular biology lab runs, and how Plasmole handles each one.
- Reading the plasmidpUC192,686 bp
- Finding restriction sitesEcoRI1 siteScaI1 site
- Simulating the digest on a gel
Each enzyme cuts once. The complete digest produces 1,783 bp and 903 bp fragments.
Cloning checks
M. Chen can pick up the same experiment.
Digest verification
Expected result
Digest pUC19 with EcoRI and ScaI.
Attach the gel image after the run and compare with the predicted bands.
Maps, primers, cloning checks and the notebook in one lab workspace.
- Maps, annotation, ORFs and restriction analysis in one editor
- Gibson, Golden Gate and restriction cloning with a simulated gel
- Primer pairs or guide sets for up to 96 targets in one batch
The work stays in the lab workspace, linked, when a student or postdoc leaves.
- Projects live in the lab workspace, not in personal accounts
- A member's constructs, primers and entries stay when they leave
- Entries link to the constructs, protocols and gels they describe
Open formats and plain answers for research IT.
- Exports in GenBank, FASTA, SBOL, ApE, PDF and JSON
- No model training on your data
- A public subprocessor list, and SIG, SIG Lite or CAIQ answers under NDA
One workspace, four jobs.
Everything at the bench, in one place.
Design, primers, cloning checks and the notebook, with an agent that runs the real tools.
See the whole lab.
The lab's shared projects, a lab board with owners and due dates, and records that stay when people leave.
Nothing leaves with people.
Work items across the lab, shared workflow templates, and one library instead of personal folders.
A review you can finish.
A public security page, the subprocessor list, and SIG, SIG Lite or CAIQ answers under NDA. Security overview
The work comes back out as a paper.
A lab's output is not a library of constructs, it is a figure, a methods section and a supplementary file. Everything here leaves in a format a journal or a co-author can open.
- 01
The map goes into the figure.
Plasmid maps export as SVG or PDF, so a map goes into a figure panel as vector art instead of a screenshot of a screen.
- 02
The methods section is already written.
Notebook entries export as PDF, Word or Markdown, carrying the steps as they were checked off and the construct, protocol and gel the entry points at.
- 03
The sequence leaves in the format a supplement takes.
GenBank, FASTA, SBOL or ApE, one construct at a time or the whole library as a ZIP.Workflow graphs export as JSON. Entries and workflows export one at a time.
- 04
The history holds up to a reviewer.
Every construct and entry keeps its version history. On a construct you can compare two versions and restore one; an entry's saved version cannot be edited afterwards, by anyone.
The part that takes months, answered up front.
Getting a new tool approved is usually slower than choosing it. A researcher can work on the free plan while that runs. Security overview
You own what you put in
You keep the rights to what you put in. Plasmole does not train, fine-tune or evaluate any model on your sequences, entries or conversations.
Nothing is locked in
Constructs export as GenBank, FASTA, SBOL or ApE, entries as PDF, Word or Markdown, maps as SVG or PDF. The whole library exports as a ZIP.
Readable without an NDA
The security page and the subprocessor list are public, so a review can start before anyone signs anything. We answer SIG, SIG Lite and CAIQ under NDA, and AI processing can be turned off for your workspace if the institution requires it.
What isn't done
A SOC 2 Type I audit is in progress and there is no report yet. Plasmole is not validated for 21 CFR Part 11 or GLP work.
How is this different from the free tools we already use?
Most free tools stop at the map or the notebook. Plasmole puts cloning checks, 96-target primer and guide batches, the notebook and an agent that runs Primer3, BioPython and BLAST in one lab workspace, and the lab owns what's in it. There's a free plan to try it.
What happens to a student's work when they leave?
It stays in the lab workspace. Their membership ends; what they made stays with the lab.
Can we bring our SnapGene files?
Yes. SnapGene (.dna), GenBank, FASTA, SBOL and ApE files upload directly.
Will it pass our IT and security review?
Send us your questionnaire. The security page lists encryption, access controls and our subprocessors, and we answer SIG, SIG Lite and CAIQ under NDA. A SOC 2 Type I audit is in progress.
Is our data used to train AI?
No. Plasmole does not train, fine-tune or evaluate any model on your sequences, notebook entries or conversations, and we can turn AI processing off for your workspace if your institution requires it.
Is it free for academic labs?
There is a free plan for individual researchers. For a whole lab, book a pilot and we'll set up the lab workspace with you.